Stem Cell Treatment for Diabetes
Diabetes in the USA refers to a group of chronic metabolic disorders characterized by high blood sugar levels over a prolonged period. The two most common types of diabetes are type 1 diabetes and type 2 diabetes.
Type 1 Diabetes: diabetes is an autoimmune disease in which the body's immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body does not produce enough insulin, the hormone responsible for regulating blood sugar levels. People with type 1 diabetes require lifelong insulin therapy to survive. Type 1 diabetes is usually diagnosed in childhood or adolescence, and its exact cause is not fully understood.
Type 2 Diabetes: diabetes is a metabolic disorder characterized by insulin resistance and relative insulin deficiency. In this condition, the body becomes less responsive to the insulin it produces, and the pancreas may not produce enough insulin to meet the body's needs. Type 2 diabetes is often associated with lifestyle factors, such as obesity, sedentary behavior, and poor dietary habits. It is more common in adults, but it can also occur in children and adolescents, especially with the rising prevalence of childhood obesity.
Key points about diabetes in the USA:
• Prevalence: Diabetes is a significant public health issue in the USA, with millions of adults and children affected by the disease. Both type 1 and type 2 diabetes contribute to the overall diabetes burden in the country.
• Health Implications: Diabetes can lead to various complications if not well managed, including cardiovascular disease, kidney damage, nerve damage (neuropathy), eye problems (retinopathy), and foot ulcers.
• Screening and Diagnosis: Diabetes is typically diagnosed through blood tests that measure blood glucose levels. Early detection and management are essential to prevent complications.
• Management: Diabetes management involves lifestyle modifications, such as a healthy diet, regular physical activity, and weight management, as well as medication (including insulin for type 1 diabetes and various oral medications and/or insulin for type 2 diabetes).
• Diabetes Education and Support: People with diabetes require ongoing education and support to effectively manage their condition. Diabetes self-management education (DSME) programs are available to provide individuals with the knowledge and skills needed to control their blood sugar levels and prevent complications.
What may this include:
1. Voltarelli JC, Couri CE, Stracieri AB, et al. Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA. 2007;297(14):1568-76. doi: 10.1001/jama.297.14.1568.
2. Bhansali A, Asokumar P, Walia R, et al. Efficacy and safety of autologous bone marrow-derived stem cell transplantation in patients with type 2 diabetes mellitus: a randomized placebo-controlled study. Cell Transplant. 2014;23(9):1075-85. doi: 10.3727/096368913X667709.
3. Hu J, Yu X, Wang Z, et al. Long term effects of the implantation of Wharton's jelly-derived mesenchymal stem cells from the umbilical cord for newly onset type 1 diabetes mellitus. Endocr J. 2013;60(3):347-57. doi: 10.1507/endocrj.ej12-0307.